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One of the most exciting developments is the use of immunotherapy in the *neoadjuvant setting*, before surgery. Studies have shown that adding immunotherapy to chemotherapy before surgery can significantly increase the chance of achieving a *pathologic complete response* (no remaining cancer cells found in the breast or lymph nodes after surgery). This is a great indicator of a positive outcome. Immunotherapy also can be used in the adjuvant setting after surgery to help prevent recurrence. Immunotherapy can have side effects. Since it boosts the immune system, it can cause the immune system to attack healthy cells and tissues, leading to inflammation in various parts of the body. These side effects can range from mild to severe and may include fatigue, skin rashes, and autoimmune disorders. Immunotherapy is a promising option, but it's essential to understand its potential benefits and risks.
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* WrestleMania 33 (2017)
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